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6374

Ampoule Filling and Sealing Machine

Main usage and features The machine is the new generation multi-position drawbench filler. Matrix bottle delivering device is adopted in the new machine which makes the ampoule filling more stable and gains lower bottle broken ratio. A new clutch device is installed to the hopper which can make non-stop ampoule delivering to reduce ampoule wasting. It also has high stability auto-stopping device when no bottle in filling position. The bottle output device abandoned the traditional delivering method, using a better way to settle the bottles to acquire a higher finish product ratio. Technical Data
Specification 1-2ml
Output 9000-12000dosage/hour
Power 380V/0.55kw
Contour Dimension 170*950*131cm
Weight 300kg
43085397523

Ampoule Filling and Sealing Machine

Introduction This ampoule filling and sealing machine is a machine recently developed by our factory in accordance with world tide and domestic situation. The machine can be used for ampoules of 1ml, 2ml, 5ml, and can fill nitrogen and seal8 ampoules simultaneously. Air purifying device of many forms can be equipped on top of the machine according to the requirement of customer. This machine can be solely used, and can be used together with ultrasonic wave cleaning machine and sterilizing tunnel drying machine as well. It has merits of high production rate, high filling precision, high qualified rate for sealing, stable and reliable running, low noise, easy and fast replacing of standard parts, and no need to adjust repeatedly, it is simplified and humanized. Technical data

Number of filling heads12
  Ampoule
  Production capability1,2ml32000pcs/h
5ml25000pcs/h
10ml19000pcs/h
rated production capability90% above production capability
loading accuracy                               ± 2% (Glass filling pump)
percent of pass≥ 98%
Power consumption2.4kw (Ac 380V/50Hz)
Nitrogen consumption3m3/h
  Fuel gas ConsumptionCity gas0.6m3/h
LPG0.25m3/h
Oxygen ConsumptionUse City gas1.8m3/h
Use LPG2.6m3/h
Suction requirement0.6m/s
External dimension: L×W×H（mm）3600×2100×2450
Net weight (kg）2500
干热灭菌

Dry Heat Sterilizer

Introduction This sterilizer is a kind of sterilizing device in full accordance with GMP of the latest version, US FDA and EU cGMP regulations. This equipment is used for the sterilization and depyrogenation of heat-resistant materials that cannot be used for moist heat sterilization, such as glass bottles, vials, glass vessels, metal containers and equipment parts. This equipment can be supplied with a set of documents in accord of FDA, which is the preferred equipment for biological and pharmaceutical companies.       Technical data
Equipment Model Door Chamber Dimension Overall Weight Control Driver Power
Volume Dimension (Unloading) Power
mm mm Kg 220V/Kw 380V/Kw
GDS-0.24 GCS-0.24 2 500*740*650/0.24m3 1770*1050*1730 750 0.5 11
GDX-0.36 GCX-0.36 2 600*750*800/0.36m3 1870*1060*2082 800 0.5 11
GDE-0.6 GCE-0.6 2 800*800*1000/0.64m3 2070*1110*2266 900 0.5 15
GDH-0.8 GCH-0.8 2 800*1040*1000/0.83m3 2070*1310*2266 1100 0.5 18
GDA-1.0 GCA-1.0 2 800*1260*1000/1.01m3 2070*1560*2266 1300 0.5 21
GDB-1.2 GCB-1.2 2 1000*1000*1200/1.20m3 2270*1310*2466 1500 0.5 21
GDF-1.5 GCF-1.5 2 1000*1250*1200/1.50m3 2270*1560*2466 1650 0.5 28
GDM-2.0 GCM-2.0 2 1000*1700*1200/2.04m3 2270*2010*2466 1800 0.5 34
GDG-2.5 GCG-2.5 2 1000*2100*1200/2.52m3 2270*2410*2466 2000 0.5 39
GDT-3.0 GCT-3.0 2 1000*2500*1200/3.00m3 2370*2300*2622 2200 0.5 46
GDL-4.0 GCL-4.0 2 1300*2050*1500/4.00m3 2620*2360*2622 2400 0.5 54
GDK-5.0 GCK-5.0 2 1300*2492*1500/4.86m3 2620*2800*2622 2600 0.5
973845947539

Emulsifier Machine

Introduction The machine has triple blender, hydraulic lift cover, high-speed homogeneity blender (Speed is 0-3500r/min, frequency speed regulation) and low-speed scraper blender (Speed is 0-40r/min, frequency speed regulation). Fast-cutting vortex emulsification blender is used in the homogenizer part, which can scrape in a low speed and automatically blend and snuggle up to the bottom and wall of boiler. The machine draws powder material by the way of vacuum in order to prevent the powder flying. The whole working procedure is operated in the condition of vacuum in order to prevent the material coming into being bubble after high-speed blending and reach the request of sanitation and asepsis. CIP cleaning system is equipped in this system. The contact part of vessel and material is made from SUS316L material. Mirror finish of the inside surface is 300EMSH. In order to ensure the stabilization of the control, the vacuum pump is the products of Germany Siemens Company, the button is produced by Japan Fuji Company, the transducer is the product of Japan Matsushita Electric Industries and the electro-control part is the product of Siemens Company. The machine is made completely according to the GMP request, which is the most advanced and most perfect cream production equipment. The machine is specially designed adopting advanced technology of oversea according to the cosmetic and ointment production technology. The machine is made up of pretreatment boiler, vacuum emulsification blending boiler, vacuum pump, hydraulic system and worktable.     The machine has easy operation, steady capability, good homogeneity, high efficiency, reasonable structure, small volume and high automation level and easily clean. Technical data

ModelEffective CapacityEmulsifyAgitatorOutside DimensionThe Merit Rate (KW)
KWr/minKWr/minLengthWidthHeightMax H
20202.20-35000.370-4018001600185027005
505030-35000.750-4027002000201527007
10010030-35001.50-40292021202200300010
15015040-35001.50-40311021202200310011
2002005.50-35001.50-40315022002200310012
3503507.50-35002.20-40365026502550360017
5005007.50-35002.20-40397028002700395019
750750110-350040-40378032003050438024
10001000150-350040-40390034003150455029
1500150018.50-35007.50-40400041003750565042
20002000220-35007.50-40485043003600/46
eye drop filling

Eye Drop Filling, plugging and Capping Machine

Introduction This eye drop filling and capping machine mainly used for eye drop production line. This machine use advanced microcomputer to control peristaltic pumps filling in high accuracy. Technical flow process: bottles feeding with sectorial star-wheel, 4 heads to fill, stoppers feeding in 4 tracks, caps feeding in 4 tracks, 4 heads for capping. These working process can insure the products in high quality. Machine mainly consists of unscrambler, bottle feeding part, sectorial star-wheel, filling part, stopper part and capping part. Characteristic Manipulator moves the nozzles to improve the stopper rate when using thin edge nozzles. Single chip system controlled peristaltic pump filling, dosage precision is high, can adjust the dosage without stopping the machine. Filling, stopper and capping monoblock machine. Space saving and simple structure. Good appearance and easy to clean. Graduator positioning is precise, running is stable can fill bottles of different size. Touch panel control panel, easy operation and high automation degree. Speed adjustable by inverter. No bottle no filling; auto stops when no caps. Technical data
Suitable bottle range 5~30mlplastic pump (change the proper change part)
Production capacity 70-120bts/min, 5-20ml bottle Dosage 5-20ml
Filling error ≤1.5％
Auto stopper ratio ≥99.5%
Bottle breakage ratio ≤0.5%
Power supply 220V 50Hz
Power 1.3Kw
Filling head 2-head filling
Compressed air pressure 0.4~0.6Mpa    25~35 L/min
Single machine noise ≤70dB
Weight ~800Kg
Dimension 2620×1250×1480(mm)
配液系统

Liquid Preparation System

Service scope:
Oral liquid preparation system
Sterile compounding system
Extraction compounding system
Cream and eye ointment compounding system
Features of compounding system
  1. For multi-tank preparation system, advanced adapter plate design process is adopted. Tank cleaning can be completely independent of pipe, so as to avoid leakage of materials, pollution and risk of false operation.
  2. Piping and equipment meets requirements of GMP production, without blind pipe and dead ends. Installation of equipment and accessories facilitates disassembly, maintenance and repair.
  3. Control system meets operation requirements of production process, and automatic control of online cleaning, sterilization, material transfer, etc. can be realized. Relevant parameters of preparation system can be monitored and recorded in real time, to ensure quality tracking and tracing.
  4. After detailed design and before construction, the whole system will be three-dimensional designed according to layout of field equipment.
Oral liquid preparation system Oral liquid preparation system includes sugar melting, initial preparation, cold storage, filtration/centrifugation, fine preparation, heating/cooling, material transfer, CIP/SIP and control system. Sterile preparation system Sterile preparation system includes large volume injection, powder injection, small volume injection, eye drops, water injection, etc. Main functions include concentrated preparation, decarbonizing filtration, diluted preparation, sterile storage, aseptic filtration, material transfer, heating/cooling, CIP/SIP and control system. Extraction preparation system Extraction preparation system includes extraction, enrichment, cold storage, water sink/alcohol sink, centrifugation, heating/cooling, material transfer, CIP/SIP and control system. Cream and eye ointment preparation system Cream and eye ointment preparation system includes material preparation, aqueous phase, oil phase, homogenization/emulsification, heating/cooling, material transfer, CIP/SIP and control system.
powder filling KFG

Powder filling, plugging and capping machine (PT-KFG series)

Introduction This powder filling machine is a new generation of high speed screw filling machine which our company developed based on the former 4 head powder filling machine. It adopts guaduator system to conduct high speed filling process. Characteristic Filling speed is high, servo motor driven, the filling precision is high. Plate type conveyor, star wheel and graduator linked together firmly, stable running and precise positioning. Different type of filling auger meet different the needs of filling different powder. PLC control the whole process, high automation degree. Touch panel control, can set the filling dosage without stopping the machine. Speed controlled by inverter. Falling bottle auto reject; no bottle, no filling; no stoppers, auto stops; insufficient stoppers alarm Auto counting function. CE certified, standard electric installation, safety guarantee on operation. Auto stop filling when filling auger touches filling nozzle and alarms. Easy to change the change part, filling dosage adjustable. Optional acrylic glass hood, laminar flow, sealed air outlet device. Optional pre-fill and after-fill nitrogen filling device. The whole machine is designed according to GMP requirements. Technical data         
Suitable bottle range 7~30ml (tubular or molded vial)
Production capacity 280~300bts/min, 10ml bottle Dosage 1g
Power supply 220V 50Hz
Total power 3kw
Filling error ≤2%
Auto stoppering ratio ≥99.7%
Bottle breakage ratio ≤0.1%
Single machine noise ≤70dB
Vacuum degree -6x10-2Mpa, 14m3/h
Weight 800kg
Dimension 2850×1000×1800(mm)
powder filling KFs

Powder filling, plugging and capping machine (PT-KFS series)

Brief introduction This powder filling machine is a kind of screw type sterile powder filling machine. It adopts two tracks, cylinder positioning, 2 head screw filling and 2 roller stopper. The servo motor controls the filling auger precisely. Characteristic 2 long chain plate conveyor, cylinder positioning, 2-head screw filling, 2-roller stopper, so the machine length is shortened. Different types of filling auger meet requirements of powders with different fluidity. Touch panel control can set the filling dosage without stopping the machine. Speed control by inverter. Falling bottle auto reject; no bottle, no filling; no stoppers, auto stops; insufficient stoppers alarm. Auto counting function. CE certified, standard electric installation, safety guarantee on operation. Auto stop filling when filling auger touches filling nozzle and alarms. Easy to change the change part. Easy to operate and disassemble. Easy to clean the key part. Optional acrylic glass hood, laminar flow, sealed air outlet device. The whole machine is designed according to GMP requirements. Technical data
Suitable bottle range 7~30ml (Tubular vial or molded vial)
Production capacity 200-250bts/min, 7ml bottle Dosage 1g
Power supply 220V 50Hz
Power consumption 1kw
Compressed air pressure 0.4~0.6Mpa    25~35 L/min
Filling error ≤2%
Auto stoppering ratio 99.90%
Speed control Speed control by inverter
Single machine noise ≤70dB
Weight 800kg
Dimension 2270×1050×1500（mm）
6393

Soft Gel Encapsulation Machine

Introduction Different from the two-step manufacturing (shaping and filling) of hard gelatin capsule, the soft gelatin capsule is made on a rotating mould in a continuous one-step operation. Gelatin skin made of gelatin and glycerol passed through two die rolls facing each other and continuously rotating in reverse cycles and forms its shape in the mould cavity. The size and shape of the soft gelatin capsule are determined by the mould cavity. Material filling and sealing of gelatin skin is carried out in the same time so that the filling process ends right before the finish of sealing. Feature
  1. The soft gelatin capsule has tidy and beautiful appearance. Compared to tablets pills, it features faster disintegration speed, higher bioavailability and convenient ingestion, storage and taking along.
  2. The capsule can cover unpleasant odor of the medicine.
  3. The capsule can be made into instant-effective, slow-releasing, enteric coated or gastro soft gelatin capsules.
  4. Both medicine with dosage form of higher oil concentration that cannot be easily made into tablets or pills and small-dosage principle agent that is not water-soluble and hard to be ingested in the digestive tract can be dissolved in proper amount of oil and made into soft gelatin capsules.
  5. Light-sensitive and unstable drugs can be filled into opaque light proof capsules to improve the stability and prevent the drug from been affected by moisture, oxygen and light in the air.
  6. Completely sealed package ensures the intactness of its content and provides counter fake function.
  7. The soft gelatin capsule can be used to make, cosmetics and paintball for simulated shooting, etc.
Technical data
Model/Data 100 200 250 315
Mould Size (mm) Dia. 80 X W: 100 Dia. 113 X W: 200 Dia. 150 X W: 250 Dia. 157 X W: 315
Mould Revolution (RPM) 0-5 Rpm (adjusted variable speed) 0-5 Rpm (adjusted variable speed) 0-5 Rpm (adjusted variable speed) 0-5 Rpm (adjusted variable speed)
Volume of Plunger Pump 0-1.5 ml (adjustable continuously) 0-2 ml (adjustable continuously) 0-2 ml (adjustable continuously) 0-2 ml (adjustable continuously)
Pump Accuracy +/-0.5% (filling volume not less than 500 mg) +/-0.5% (filling volume not less than 500 mg) +/- 0.5% ~ 1.5% +/- 0.5% ~  2%
Pump Type 8 plunger pump 14 plunger pump 20 plunger pump 24 plunger pump
Production Capacity 4#OV capsule 30,000pills/hrs (4.0 RPM) 8#OV capsule 62,400pills/hrs (4.0RPM) 8#OV capsule 115,440pills/hrs(4.0RPM) 20#OB capsule      58,800(4.0RPM) 8#OV capsule     150,960 pills/hrs (4.0RPM)
Power Supply 1.8 Kw, 360V 3 phases (can be modified as user’s requirement.) 12 Kw, 360V 3 phases (can be modified as user’s requirement.) 12 Kw, 360V 3 phases (can be modified as user’s requirement.) 12 Kw, 360V 3 phases (can be modified as user’s requirement.)
Weight 400 Kg 1,300 Kg 1,500 Kg 1,500 Kg
Dimension (LxWxH)mm 1440x660x1350 2000x910x1900 2040x960x1900 2100x1130x1900
6397

Steam Sterilizer (ampoule/vial)

Introduction Ampoule Steam Sterilizer is mainly used for the sterilization, leak test and washing of ampoule, syrup and IV solution with small capacity. It adopts pressure steam as sterilizing medium to achieve the uniform sterilization between 105℃～127℃. This sterilizer adopts heating mode of displacement and exhausting from multi-points to ensure the through elimination of cold air in chamber, uniform and rapid heating and eliminate the dead corner caused by the existing cold air. Leak test by vacuum and color water is adopted to improve the detection rate of waste after sterilization, meanwhile provides the documents system that meets 2010 version GMP requirement. Technical data
Equipment Model Door Trolley Chamber Dimension Overall Weight Clean Deionized Clean C A Control Driver Color
Volume Dimension (Unloading) Steam Water Water Power Power Water
(Option)
mm mm Kg Kg/cycel L/cycel L/cycel Nm3/h 220V/Kw 380V/Kw L/cycel
XG1.SDE-0.6 2 1 1200*610*910/0.67m3 1490*1390*1940 1500 28 260 230 5.8 0.5 2 500
XG1.SDH-0.8 2 1 1450*610*910/0.80m3 1742*1390*1940 1600 34 310 280 7.7 0.5 2.9 650
XG1.SDA-1.0 2 2 1700*610*910/0.94m3 1992*1390*1940 1800 48 350 280 9.6 0.5 2.9 850
XG1.SDB-1.2 2 1 1500*680*1180/1.20m3 1812*1465*1940 2300 58 400 280 12 0.5 2.9 1000
XG1.SDC-1.5 2 2 1870*680*1180/1.50m3 2182*1465*1940 2550 74 650 400 14.4 0.5 4.6 1250
XG1.SDD-2.0 2 2 1700*1000*1200/2.04m3 2062*1792*1990 2650 107 700 400 19.2 0.5 4.6 1700
XG1.SDG-2.5 2 2 2100*1000*1200/2.52m3 2462*1792*1990 2900 138 750 400 24 0.5 4.6 2100
XG1.SDN-3.0 2 3 2500*1000*1200/3.00m3 2862*1792*1990 3250 159 800 400 28.8 0.5 6.05 2500
XG1.SDO-3.5 2 3 2900*1000*1200/3.48m3 3262*1792*1990 3450 175 1060 400 33.6 0.5 6.05 3000
XG1.SDF-5.0 2 4 4200*1000*1200/5.04m3 4562*1792*1990 4300 277 1850 350 48 0.5 6.2 4300
XG1.SDQ-6.0 2 5 5200*1000*1200/6.24m3 5562*1792*1990 4500 347 2000 350 57.6 0.5 6.2 5500
6395

Steam Sterilizer (D series)

Introduction PT-D Series Steam Sterilizer is a top grade sterilizing device in full accordance with GMP regulations of the newest version. It is widely used for sterilization of biological products, vessels, sterile gown, medical instruments and dressing, which require high sterilization effect in areas of biology engineering, medical hygiene, animal laboratory and pharmaceutical industry, meanwhile provides the documents system that meets 2010 version GMP requirements. Technical data
Equipment Model Door Chamber Dimension/Overall Dimension Weight (Unloading) Plant Steam Pure Steam Clean Water C A Driver Power
mm Kg Kg/cycel L/cycel L/cycel L/min 380V/Kw
XG1.DWS-0.24D XG1.DTS-0.24D 1 670*600*600/0.24m3/ 932*1235*1780 600 15 5 250 36 1.45
XG1.DWS-0.24 XG1.DTS-0.24 2 670*600*600/0.24m3/ 982*1235*1780 650 15 5 250 36 1.45
XG1.DWX-0.36D XG1.DTX-0.36D 1 994*600*600/0.36m3/ 1256*1235*1780 670 18 7 250 36 1.45
XG1.DWX-0.36 XG1.DTX-0.36 2 994*600*600/0.36m3/ 1306*1235*1780 720 18 7 250 36 1.45
XG1.DWE-0.6D XG1.DTE-0.6D 1 1170*610*910/0.65m3/ 1412*1306*1940 1400 20 10 300 36 2.35
XG1.DWE-0.6 XG1.DTE-0.6 2 1170*610*910/0.65m3/ 1462*1306*1940 1450 20 10 300 36 2.35
XG1.DWH-0.8D XG1.DTH-0.8D 1 1450*610*910/0.80m3/ 1692*1306*1940 1600 22 12 300 36 2.35
XG1.DWH-0.8 XG1.DTH-0.8 2 1450*610*910/0.80m3/ 1742*1306*1940 1650 22 12 300 36 2.35
XG1.DWA-1.0D XG1.DTA-1.0D 1 1700*610*910/0.94m3/ 1942*1306*1940 1750 25 15 400 36 2.35
XG1.DWA-1.0 XG1.DTA-1.0 2 1700*610*910/0.94m3/ 1992*1306*1940 1800 25 15 400 36 2.35
XG1.DWB-1.2D XG1.DTB-1.2D 1 1500*680*1180/1.20m3/ 1762*1465*1940 1950 25 15 400 36 3.85
XG1.DWB-1.2 XG1.DTB-1.2 2 1500*680*1180/1.20m3/ 1812*1465*1940 2000 25 15 400 36 3.85
XG1.DWF-1.5D XG1.DTF-1.5D 1 1870*680*1180/1.50m3/ 2132*1465*1940 2150 28 18 500 36 3.85
XG1.DWF-1.5 XG1.DTF-1.5 2 1870*680*1180/1.50m3/ 2182*1465*1940 2200 28 18 500 36 3.85
XG1.DWM-2.0 XG1.DTM-2.0 2 1700*1000*1200/2.04m3/ 2062*1792*1990 2650 40 30 600 36 3.85
XG1.DWG-2.5 XG1.DTG-2.5 2 2100*1000*1200/2.52m3 2800 45 35 650 36 4
XG1.DWT-3.0 XG1.DTT-3.0 2 2500*1000*1200/3.00m3 3100 55 45 650 36 4
XG1.DWO-3.5 XG1.DTO-3.5 2 2900*1000*1200/3.48m3 3350 60 50 750 36 4
XG1.DWL-4.0 XG1.DTL-4.0 2 3400*1000*1200/4.08m3 3700 65 55 750 36 4
XG1.DWK-5.0 XG1.DTK-5.0 2 4000*1000*1200/4.80m3 4100 80 70 850 36 5.5
 
tunnel

Sterilization Tunnel

Introduction This tunnel oven is a hot air circulation tunnel oven our company developed to meet the need from the market by referring similar product abroad. It integrates high technology. This oven can reach the standard of sterilization and removing pyrogen after many years of pharmaceutical factory usage and test before leaving the factory. The heat distribution is average inside the box chamber. Characteristic
  1. There are HEPA filter in preheating section, sterilization section, cooling section and the entire tunnel. Clean degree is high.
  2. Hot air circulation has the advantage of energy-saving and good temperature homogeneity. The heat distribution is ±5℃.
  3. With frog validation connector. (DOP)
  4. Stainless steel sheet covers the frame, good appearance. Oven box and net conveyor is made of S.S.304 or S.S.316L
  5. HEPA filter choose international brand, adopts built-in installation, good sealing effect.
  6. Choose LCD touch panel (TP) and controller (PLC) to control the heating and operation technical parameters precisely.
  7. With parameter separate display function, auto print record and error alarm and display function.
  8. The air flow is controlled by electric pressure gauge, can auto balanced.
  9. Adopts chain wheel to drive the net conveyor, avoid any conveyor deflection effect.
  10. Complete 100 class protection, air inlet and air outlet with clean laminar flow protection, avoid outer air goes in the machine. Ensure working chamber under 100-class status.
  11. Optional remote control function and fan ‘ON DUTY’ function.
  12. Optional net conveyor CIP system (ultrasonic wave cleaning).
  13. With air cooling or 2 class water cooling.
  14. The whole machine is easy to clean and without dead angle. The designing and fabrication fully comply with GMP regulations.
    Production capacity
Model Production capacity
500 7ml tubular vial 100~140 bts/min
700 7ml tubular vial 250~300 bts/min
900 7ml tubular vial 500~600 bts/min
1200 7ml tubular vial  900~920 bts/min
        Technical data
Suitable bottle range 1~20ml,2~500ml (ampoule, tubular or molded vial)
Sterilization temperature 350℃
Sterilization time ≥ 5min~7min
Net conveyor speed 50~250mm/min
Bottle outlet temperature ambient temp (ambient) +10℃
Clean degree A(class)
Cooling type Air cooling or water cooling
Power supply 380V 50Hz
Electric heater Quartz glass heater or s.s. Heater
Single machine noise ≤70dB
Fan Ydf type low noise fan 2 units
Dimension (L*W*H) 500: 4500×1630×1900 (mm)
700: 6000×1820×1900 (mm)
900: 8000×2020×1900 (mm)
Power 500: 50kw
700: 72kw
900: 90kw
1200: 120kw